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Neuroprotective efficacy of the peroxisome proliferator-activated receptor -selective agonists in vitro and in vivo
Approval for Diabetes and Weight Management Over the past decade, three GLP-1/GIP receptor agonists liraglutide, semaglutide, and tirzepatide initially approved by the FDA for adults with type 2 diabetes, have also gained FDA approval for chronic weight management in people without diabetes, provided they meet specific criteria: a BMI of 30, or 27 with at least one weight-related condition such as hypertension, dyslipidemia, or type 2 diabetes
Vardiyan R, Ezati D, Anvari M, Ghasemi N, Talebi AJC, Medicine ER
Pharmaceutics 13 , 15991607 (2016)
Potential Side Effects While GLP-1 medications are generally well-tolerated, potential side effects include: Nausea Diarrhea Vomiting Constipation Abdominal pain Most side effects are mild and improve with continued use
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