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The most common side effects with the 12 mg dose were nausea (43.2%), diarrhea (33.1%), constipation (25.0%), and vomiting (20.9%)
J Psychiatry Neurosci 39(1):621
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This unexpected result raised the possibility that reduced lag-2 expression, either directly or through the resulting decrease in GLP-1/Notch activity, led to an increase in DTC-AC
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