GSH inhibits PSC activation induced by high glucose via the ROS/TGF/SMAD pathway in vitro The above results indicated an increase in pancreatic fibrosis in rats treated with LOsG, which was accompanied by an increase in ROS/TGF/SMAD signalling, and PSC proliferation and activation, which were all prevented by GSH
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Athauda D, Maclagan K, Skene SS, Bajwa-Joseph M, Letchford D, Chowdhury K, et al