Children presenting neurological signs or symptoms, those unable to take oral medication, individuals with known malabsorption syndromes, infants under 6 months old, and patients using medications that may interfere with vitamin B12 absorption are typically treated with a parenteral protocol (1)
patents and other international patents
Interestingly, knockdown of RIPK1 exacerbated ZEA-induced toxicity but did not diminish the protective effect of scutellarin, implying potential pathway redundancy or alternative mechanisms of action
This work was funded by Korea Institute of Planning and Evaluation for Technology in Food, Agriculture, Forestry and Fisheries, RS-2025-02218354, Sun-Ki Kim, Korea Evaluation Institute of Industrial Technology, RS-2025-02307907, Sun-Ki Kim, Chung-Ang University, Graduate Research Scholarship (Academic Scholarship for the College of Biotechnology, Sang-Hun Do, Natural Resources) in 2024, Sang-Hun Do
By regulating PTEN and the PI3K/AKT axis, ER-36 migrates the apoptotic death of tubular cells under HG conditions (122)
It is potent enough to serve as a clinical provocative agent