Weight regain after stopping GLP-1 analogue treatment is possible if healthy lifestyle habits are not maintained
Patients with A1C 8% at screening had their background basal insulin dose reduced by 20% at the start of the trial to limit potential risk of hypoglycemia
A diferencia del GLP-1, el GIP aumenta la secrecin de glucagn por las clulas alfa, estimula la lipognesis, inhibe la liplisis en los adipocitos y mejora la captacin de cidos grasos 4
Possible causes: dead space accumulation (discussed above), inaccurate water volume at reconstitution (more water means more dilute, means more volume per dose, means fewer doses from the same amount of peptide), or air in the vial displacing solution
doi: 10.18632/oncotarget.12186 36
Work your way up to 1 mg over months