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Postgrad Med 127(8):818-26

View image online ( illustration showing action of a GLP-1 receptor agonist For the first time, a pharmacotherapy for overweight and obesity has been shown to reduce cardiovascular events in patients with established cardiovascular disease (CVD) in the absence of type 2 diabetes

Phase 2 trials reported 24.2% average bodyweight loss at highest doses over 48 weeks (NEJM)

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