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Formulation can improve both stability and absorption, but even with the most advanced formulation, the only oral GLP-1 available today achieves roughly one percent absorption, and uptake varies widely between patients, making consistent dosing a challenge

A compressed tablet has no comparable structure to lose, which is why the article treats temperature control as part of the treatment

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Concluding remarks In this review, we have presented some premises surrounding the potential of GLP-1 receptor agonists for exerting antidepressant effects by outlining their impact on some key processes, which are known to be involved in the pathogenesis of this mental illness