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The New England journal of medicine 375 , 311322 (2016)

Drosophila glutathione S-transferases

Research published in The New England Journal of Medicine and replicated across multiple clinical trials consistently shows that weight loss from GLP-1 therapies follows a predictable curve: rapid early loss followed by a plateau, typically between weeks 12 and 24, before additional loss resumes or stabilizes

Kim et al., 2021

In the context of patients with MASLD and diabetes, only one clinical study evaluated the benefits of beinaglutide treatment over 24 weeks compared to recommended standard lifestyle management for T2DM

Body weight management and safety with efpeglenatide in adults without diabetes: a phase II randomized study