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doi: 10.1099/ijs.0.2008/000810-0 57 ParkerBJWearschPAVelooACMRodriguez-PalaciosA
But heres what we know from recent research: A 2025 study presented at ENDO showed that postmenopausal women using tirzepatide plus hormone replacement therapy (HRT) lost significantly more weight (17% total body weight) compared to women using tirzepatide alone (14%)
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Stress triggers the release of cortisol and adrenaline, hormones that can reduce insulin sensitivity, resulting in greater hunger, cravings, and weight gain
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