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It is indicated for adults with obesity (BMI of 30 kg/m^2 or greater) and adults who are overweight (BMI of 27 kg/m^2 or greater) with at least one weight-related medical condition, such as high blood pressure, T2D, or dyslipidemia

Educational framing keeps expectations realistic and clinically grounded

Mechanistically, GLP-1 receptor agonists improve endothelial function, cause vasodilation, reduce systemic vascular resistance, lower blood pressure, reduce inflammation, and favorably affect lipid profiles

for example, clinical trials show constipation occurs in approximately 24% of patients taking Wegovy (semaglutide 2.4mg), with lower rates typically seen with dulaglutide and standard-dose semaglutide

The product type segment is divided into semaglutide, liraglutide, exenatide, dulaglutide, and others, with semaglutide taking the lead in 2024 with a market share of 58.4%