"BPC 157 and angiogenesis: The potential of promoting new blood vessel formation in injury repair." Annals of Anatomy , 196(6), 376383
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This absence of formal research means that any combined use is based on extrapolation from individual drug studies, theoretical pharmacology, and anecdotal clinical experience rather than robust evidence
But declining serum levels do not automatically mean topical or injectable supplementation restores tissue-level function
Studies on topical delivery typically show effects concentrated in the epidermis and upper dermis
Some patients interested in broader peptide-based approaches to inflammation and recovery also explore BPC-157 for mental health , particularly because of ongoing interest in the gut-brain axis and neuroinflammation