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They work through completely different pathways, so there's no receptor overlap to manage
The evidence is real but modest: trial data shows more fat loss than placebo over 12 weeks, not dramatic transformation
While primarily known for its energy-boosting capabilities, Vitamin B12 also has a significant impact on metabolism and weight loss
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Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease
