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Morita M, Gravel SP, Hulea L, et al

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Theyve also noticed an association between the MTHFR mutation and psychiatric disorders and neurological diseases like depression, autism spectrum disorder, Parkinsons disease and Alzheimers disease.[2] Because methylfolate is involved in DNA repair and replication, and it plays an important role in glutathione production and detoxification, an MTHFR mutation might also be associated with higher cancer risk

10,15,91 Of current interest is estetrol, which is a natural estrogen that spares the endometrium, while being an estrogen receptor agonist in the tissues, including the skin, that deteriorate following the loss of estradiol in the post-menopausal period

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