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GLP-1, a hormone primarily secreted from the ileum in response to nutrient intake, exerts multiple metabolic effects including appetite suppression, delayed gastric emptying, enhanced insulin secretion, and inhibition of glucagon release [4]
Larsen, Fledelius, Knudsen,Tang-Christensen
Schmidt-Supprian, M
R., Chasan-Taber, L., Albright, A
It means the compounds effects are transient and it clears the system quickly once administration stops
While its rare for nausea to be severe, this means that the dose probably needs adjustment and it's important for that person to talk with their healthcare provider
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