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Retatrutide will likely still have the low chance of severe issues like: Acute pancreatitis Gallbladder problems Severe GI events Potential for Allergic reactions A warning about thyroid tumors: No cases of medullary thyroid cancer or C-cell hyperplasia were reported in retatrutide trials, but GLP-1 receptor agonists as a class carry preclinical warnings based on rodent studies

The SELECT trial established cardiovascular risk reduction as a class effect, leading to expanded indications for these medications ^1

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