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They can damage cells in the body
TRIUMPH-4 Phase 3 (68 weeks, 12mg, 445 patients): 28.7% weight loss, with 58.6% achieving 25% surgical-level outcomes
Its safety in individuals over 75 years of age is not established
J Lipid Res (2006) 47(12):272637.10.1194/jlr.M600299-JLR200 131 OzcanUCaoQYilmazELeeAHIwakoshiNNOzdelenEet alEndoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
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