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A 2025 review in The Journal of Bone and Joint Surgery further emphasized that patients with obesity can still achieve meaningful functional improvement, but require preoperative medical optimization, weight management, consideration of bariatric surgery and GLP-1 receptor agonists, and multidisciplinary perioperative planning (Koh et al., 2025)

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Whatever its source, one of the major circuit functions of striatal GABA co-transmission with DA appears to be binding auto-receptors to modulate phasic DA release (Patel et al., 2024)

When people talk about peptides for skin health, hair growth, and recovery, one name comes up consistently: GHK-Cu, often referred to as the glow peptide