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Questions persist about bioavailability, tissue penetration, duration of effect, and whether benefits observed in cell and animal models translate reliably to human skin, joints, or systemic health

In addition to its antidiabetic results, it was also found to achieve cardiac protection by activating the AMPK pathway [225]

Mutations in mtDNA caused by ROS can further exacerbate mitochondrial dysfunction, creating a vicious cycle of oxidative stress and energy deficits (40, 41)

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Yan Y, Yuan N, Chen Y, Ma Y, Chen A, Wang F, et al

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