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8-week on, 4-week off example: Weeks 1-2: Assessment and dose finding (every other day) Weeks 3-6: Optimization phase (3-5 times weekly) Weeks 7-8: Maintenance (3 times weekly) Weeks 9-12: Complete break, no DSIP During the off period, focus on sleep hygiene fundamentals: consistent wake times, light exposure management, temperature optimization, and stress reduction
ISBN 978-1-4419-7103-6
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Of these differentially expressed genes (DEG), 944 were upregulated and 1734 downregulated
Symptomatic treatment should be provided
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