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Hydroxocobalamin tends to remain in the body longer and is more readily converted to the active coenzyme forms of B, which can make it effective for maintaining B levels

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First in the methionine synthase reaction, homocysteine is converted to methionine allowing for the recycling of 5-methyl-tetrahydrofolate (THF) to N5,10 methylene-THF which is needed for the de novo synthesis of thymidylic acid and ultimately, for DNA formation