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Considering the rapid progress of bispecific antibody based molecules 22 , this lack of clinical data for any peptide-antibody fusion likely reflects the significant technical challenges in the development of such molecules
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One consequence of this popularity is that despite their high cost, the GLP-1 agonist medications have seen demand outstrip their supply resulting in shortages making their availability to treat diabetes more limited
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A hydrolytic -glutamyl transpeptidase from thermo-acidophilic archaeon Picrophilus torridus : binding pocket mutagenesis and transpeptidation
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