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It is present in every cell but especially concentrated in the liver where it plays a major role in phase II detoxification, the stage in which glutathione binds to toxic molecules to prepare them to be removed from the body
Administration of DOX increases copper-zinc superoxide dismutase (supporting the theory about DOX-induced superoxide radical production)
Patients who skip the escalation or increase doses too quickly are significantly more likely to experience severe nausea, vomiting, and other gastrointestinal side effects that may lead them to discontinue treatment entirely
Les chercheurs ont fait ce constat au sein de diffrentes populations
-glutamylcysteine synthetase (GSH1)
E.MooteP
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