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HIGHLIGHTS TriNetX cohort: adults with cirrhosis initiating GLP-1 after diagnosis
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The high levels of insulin have been shown to reduce the levels of the Insulin-like growth factor (IGF) binding protein, which can tightly bind to IGFs, resulting in excessive free IGF-1 in cells and tissues
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They found that the odds of discontinuing the medications were highest for patients younger than 65 years and for those with only obesity
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