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Food and Drug Administration (FDA) has a boxed warning for thyroid cancer and MEN 2 syndrome

Risk of an infeasible or underpowered trial Given the aforementioned logistical, ethical and financial issues, a 2-arm RCT comparing the use of GLP-1 drugs for cancer prevention may not be feasible in the real world

Cost concerns The list prices for Mounjaro and Zepbound are $1,079.77 and $1,086.37 per month, respectively

Results will vary by individual and dosage, but a review of studies found that the maximum dose (2.4 mg) showed more promising results than lower doses

Yang J, Chen C, McLaughlin T, Wang Y, Le YZ, Wang JJ, et al

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