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Sham-operated rats underwent the same surgical procedure except for the MCA occlusion

Rare but serious reactions such as allergic responses may occur in sensitive individuals

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Going 5 days one week and 10 days the next creates fluctuating blood levels that can worsen side effects and reduce effectiveness

It is particularly common in individuals with certain risk factors, including those who have undergone gastric or small intestine resections, have inflammatory bowel disease, use metformin or proton pump inhibitors, follow a vegan diet, or are older than 75 years