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When your digestive system breaks down food, or when you are exposed to environmental toxins like cigarette smoke or radiation, you produce molecules with unpaired electrons called free radicals
Their immune system forgot how to call off the attack
The PPAR agonists rosiglitazone and pioglitazone were recently found to reduce the levels of 2-HG and H3K4me3 in the colon of mice with colitis and to regulate GSH and ROS levels in lamina propria lymphocytes by modulating GLS1/2-HG/H3K4me3 signaling in mouse models of colitis and asthma (52) ( Table 1 )
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Leuenberger, P
Functionalized liposomes for targeted breast cancer drug delivery
