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elegans exhibited enhanced mitochondrial clearance and reduced levels of oxidative stress, both of which contributed to the observed lifespan extension (Reference Ryu, Mouchiroud and Andreux15)

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Functional GTP cyclohydrolase 1 exists as a homodecamer that consists of two tightly associated dimers that each comprise a pentameric complex of the GTP cyclohydrolase 1 monomers

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