A vial that has been frozen should not be used, as ice crystal formation can damage the protein structure
Other common gastrointestinal side effects (affecting between 1 in 10 and 1 in 100 patients) include: Diarrhoea Vomiting Constipation Abdominal pain or discomfort Dyspepsia (indigestion) Flatulence and bloating These effects are generally dose-dependent , meaning they are more likely to occur or worsen when the dose is increased
GLP-1 slows gastric emptying, increases satiety, reduces appetite through central nervous system effects, and enhances glucose-dependent insulin secretion while suppressing glucagon release
Many commercial products contain both types in varying ratios, offering balanced support for overall digestive function
As DiMarchi explains, glucagon, one of the hormones that reta mimics, is thermogenic, meaning that it stimulates energy utilization. Because users are both eating less, and burning more, the effects are greater
Both medications can be expensive without insurance, but most insurance companies will cover at least part of the cost if the medication is deemed necessary by your healthcare provider