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Patients interested in the Phase 3 programme should check ClinicalTrials.gov or the EU Clinical Trials Register for current trial identifiers, eligibility criteria, and participating sites, as the programme name and trial details should be verified against these authoritative registers
Body aches and joint pain have been reported with tirzepatide use, but these affect muscles and joints, not the thyroid gland
It means it should be framed as unfinished
The trial validates an oral maintenance strategy following successful injectable-led weight loss, promises to improve patient convenience and adherence through a simple daily pill, and does so with a reassuring safety profile
In addition, in a rat model of IBS, intraperitoneal administration of exendin-4 normalized stress-induced defecation and visceral pain sensitivity, without affecting centrally regulated anxiety-like behaviors [56]
Accessed February 17, 2026
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