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Oxidative stress, characterized by an imbalance between ROS and antioxidant defenses, is a significant pathogenic factor in asthma that leads to the activation of MAPK pathways, including the ERK, JNK, and p38 MAPK pathways, which are pivotal in mediating inflammatory responses [118,119,120]

J Pharmacol Exp Ther 2003

Clinical trials are ongoing to determine its safety, optimal dosing regimens, and long-term effects, particularly for those using the peptide outside of approved medical applications

All these symptoms are interconnected through the bonds of oxidative stress and collagen degradation