A decrease in MTHFR enzyme activity leads to an increase in homocysteine levels, which can negatively impact the absorption and utilization of vitamin B12 in the body
PMID: 40005999 | doi:10.3390/ph18020185 McGuire FP et al
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Homocysteine: B12, along with folate and B6, helps break down homocysteine, an amino acid that at high levels is associated with heart disease and stroke
GLP-1RAs have been shown to improve liver health in patients with NAFLD and type 2 diabetes, as well as non-alcoholic steatohepatitis (NASH) [13, 29]