vision changes tirzepatide macular degeneration NEJM Editorial Fellow Katerina Lin, MD, unpacks the science behind a study on Can Tirzepatide Cause Blindness? What

You should avoid using them together unless specifically advised by a healthcare professional who is prescribing you both of these medications

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Wegovy slows gastric emptying (an effect that diminishes over time), increases feelings of fullness, and reduces appetite, leading to decreased caloric intake and subsequent weight loss

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This triggers systemic (system-wide) inflammation, increasing the risk for food sensitivities, inflammation, pain, brain degeneration, and autoimmune disease

Glucocorticoids suppress glp-1 secretion: possible contribution to their diabetogenic effects