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In zebrafish larvae, the positive control diazepam at 18 M was able to reduce the severity of the seizures (Fig

The researchers proposed that the compounds effects on muscle function operate through boosting NAD+ levels by inhibiting NNMTs consumption of nicotinamide, more substrate is available for NAD+ synthesis via the salvage pathway, supporting mitochondrial function and energy metabolism in aged skeletal muscle

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Jose et al

De Wit, C