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Additionally, liraglutide improved nociceptive thresholds and reversed histopathological damage of the sciatic nerve in diabetic rats induced by nicotinamide and streptozotocin [11]

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Since cytokines can also regulate the activity of tryptophan catabolism in astrocytes and microglia, this finding corresponds to the alterations in the kynurenine pathway observed in the brains of individuals with schizophrenia (186)

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