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BMI Outcomes: Crossing the Obesity Threshold 65.3% of patients on the 12mg dose dropped their BMI below 30 moving from the "obese" to the "overweight" or "normal" BMI category

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Tsaousidou E, Paeger L, Belgardt BF, Pal M, Wunderlich CM, Brnneke H, Collienne U, Hampel B, Wunderlich FT, Schmidt-Supprian M, Kloppenburg P, Brning JC (2014) Distinct roles for JNK and IKK activation in Agouti-related peptide neurons in the development of obesity and insulin resistance