In general, he added, patients who have diabetes have an underlying pancreatic dysfunction, so that is huge confounding bias as to why they may develop pancreatic disease. In yet another poster presentation at the meeting, Fernando Gil Lpez, also of Mayo Clinic, and colleagues conducted a systematic review and meta-analysis involving 16 studies, and a pooled total of more than 6 million patients in routine clinical settings, showing no significant increase in the risk for acute pancreatitis among those who were and were not treated with GLP-1 RAs (adjusted hazard ratio, 1.11)
Nutrients 11(7):1591
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Some serious side effects of Ozempic may include: Pancreatitis, which is inflammation of the pancreas that can cause severe stomach pain Hypoglycemia, or low blood sugar levels, which may cause symptoms like dizziness, sweating, confusion, and headache Thyroid tumors, including a rare risk of cancer, especially in people who have a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2) Worsened kidney problems, including kidney failure, especially in people with pre-existing kidney disease who experience dehydration with Ozempic Allergic reactions with severe symptoms, including swelling of the face, lips, tongue, or throat, difficulties breathing or swallowing, severe rash or itching, fainting or feeling dizzy, and very rapid heartbeat Gallbladder problems with symptoms such as pain in the upper stomach (abdomen), yellowing of the skin or eyes (jaundice), fever, and clay-colored stool Talk to your doctor about these risks before starting Ozempic, especially if you have a history of pancreatitis, kidney disease, or thyroid cancer

By mimicking both hormones, tirzepatide helps reduce appetite and food intake, promoting weight loss, as noted in Eli Lilly-sponsored studies
Slower digestion: Delayed stomach emptying may help extend feelings of fullness