In moderate amounts, it can actually help prevent migraines, which is why it is included in some migraine medications
Larger and longer-term studies will give a clearer picture of its safety, tolerability, and how it compares in real-world use
Malnutrition in older adults: screening and determinants
The purpose of this review is to comprehensively summarize the multidimensional biological effects of the carnitine pool beyond its traditional role in fatty acid oxidation and to summarize the systemic effects mediated by carnitine/acylcarnitine to provide new perspectives for pharmacological research and treatment innovation and new strategies for the prevention and treatment of a variety of diseases
Metabolic Effects of DPP-4 Related to Its Enzymatic Activity Despite DPP-4 having a relatively restricted substrate preference (Figure 1), a large number of peptides, proteins, and chemokines still fulfill the criteria and could be predicted to be suitable substrates, and indeed, many have been shown to be cleaved by DPP-4 in pharmacological kinetic, in vitro or animal studies, often using high substrate concentrations (3638)
doi: 10.3389/fimmu.2025.1604652 Received 02 April 2025 Accepted 23 May 2025 Published 06 June 2025 Volume 16 - 2025 Edited by Zhengyu Jiang, Second Military Medical University, China Reviewed by Feng Zhang, Nanjing University of Chinese Medicine, China Fangyang Fan, Beijing University of Chinese Medicine, China Updates Copyright 2025 Xia, Li, Shi, Sun and He