GLP-1 drugs are a class of medications that mimic the hormone glucagon-like peptide 1 (GLP-1)
Nearly 70% of the patients achieved an A1C of less than 7%comparable to liraglutide 1.8 mg PIONEER 4 study design 1,6 In a double-blind, double-dummy trial with a primary endpoint of mean change in A1C from baseline to 26 weeks, 711 adult patients with type 2 diabetes on metformin alone or metformin with an SGLT-2i were randomized to RYBELSUS 14 mg (n=285), liraglutide 1.8 mg subcutaneous injection (n=284), or placebo (n=142), all once daily
Kernan KF, Carcillo JA
Focus on Bioavailability If you decide to take glutathione, look for "liposomal" or "acetylated" versions
Kratz F, Drevs J, Bing G, Stockmar C, Scheuermann K, Lazar P, Unger C: Development and in vitro efficacy of novel MMP2 and MMP9 specific doxorubicin albumin conjugates
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