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We have seen that semaglutide, a medication that mimics the action of GLP-1 to regulate blood sugar and reduce appetite, can potentially enhance the weight loss and glycemic control benefits of the ketogenic diet, a low-carb, high-fat diet designed to induce ketosis

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Early research in animals found that it promoted fat loss

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Participants on higher doses achieved substantial total body weight loss by the six-month mark (see the clinical evidence section below for specific figures)