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E12 embryos: n = 12 Slc25a39 fl/fl or Slc25a39 fl/- , n = 7 ErGFP-cre +/- Slc25a39 fl/- , n = 4 ErGFP-cre +/- Slc25a39 fl/fl

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The compound was well tolerated with no evidence of genotoxicity, indicating its potential as a therapeutic agent for type 2 diabetes and obesity in humans