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In the rodents, higher doses went with lower body weight and blood sugar, and the glucagon pathway went with less liver fat
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These drugs have shown promising results for many people, but scientists are still learning about themand theres much we still dont know about their safety and side effects
Sources Lilly - What to know about retatrutide (updated March 2026) Lilly - TRIUMPH-4 Phase 3 retatrutide results on weight loss (December 11, 2025) Lilly - TRANSCEND-T2D-1 Phase 3 retatrutide results in type 2 diabetes (March 19, 2026) Lilly - TRIUMPH Phase 3 trial listing Jastreboff AM et al
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Ross Grossman, LMFT, is a licensed marriage and family therapist in California with 40 years of clinical experience
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