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Most of the GSH (8085%) is stored in the cytosol, 1015% in the mitochondria (with an equal concentration between matrix and cytosol, thus requiring specific transport systems) and a small part in the endoplasmic reticulum (ER) (1, 6, 7)
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Acknowledgements The authors are grateful for the encouragement of Professor Jie Bai to undertake this review
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Environment-responsive release: pH-sensitive nanocarriers (e.g., FeO/chitosan/TiO 2 composites) trigger drug release in acidic microenvironments (e.g., inflammation sites and crystal deposits), enhancing local efficacy (Mohamadi Bian and Moghadam, 2025
doi: 10.1016/j.bj.2023.100677 144
