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Synthetic formulations mimic this effect in tissues throughout the body

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GIP receptors in skeletal muscle may also reduce protein breakdown during caloric restriction, part of why tirzepatide shows slightly better muscle preservation than semaglutide at matched weight loss

A randomized, phase 3, open-label trial comparing the effect of the addition of tirzepatide once weekly versus insulin lispro (U100) three times daily in participants with type 2 diabetes inadequately controlled on insulin glargine (U100) with or without metformin (SURPASS-6)

Glutathione helps to prevent oxidative damage by protecting cell membranes, tissues and lipids

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