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Acute systemic LPS injections induce pronounced but reversible changes in astrocyte gene expression in the prefrontal cortex, along with an approximate 25% decrease in astrocyte branch and process volumes, but with few currently detectable changes in astrocyte physiology and basic preservation of astrocyte core homoeostatic functions such a potassium buffering

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Doses and half-lives are conventions, not pharmacology

Zinc availability regulates exit from meiosis in maturing mammalian oocytes

The pattern is striking: GHK-Cu shifts gene expression from a "damaged/aged" profile toward a "healthy/younger" profile

In general, the toxicity of nitrenium ions is clinically relevant since these electrophiles possesing DNAbinding ability are responsible for carcinogenicity of aromatic amines