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Analyses of publicly available T1D-related datasets 34,35 showed that MOTS-c (mtRNR1) expression levels significantly decrease following treatment with SASP-related cytokines (FDR of 0.032, IFN-, IL1, TNF 14

Metoclopramide and erythromycin are the two most commonly used agents used to manage gastroparesis and there is potential that the GLP-1 agonists will oppose the prokinetic effects of these agents Corticosteroids Corticosteroids are notorious for raising blood sugars which could directly oppose the blood sugar lowering effects of GLP-1 agonists

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