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The thigh may produce less nausea based on one clinical study, while the abdomen may provide slightly faster peak absorption

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The switching timeline from tirzepatide to retatrutide and the dosage schedule after high-dose tirzepatide require careful planning with a researcher

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In one study of 3,127 adults with obesity but not diabetes, those taking the highest dose lost an average of 27 pounds, or 12.4 % of body weight, over 72 weeks

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Its not certain if that was due to the weight loss, but a recent observational study linked GLP-1 drugs to an increased rate of kidney stones

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Check with your doctor right away if you have a bloody urine, decreased urine output, muscle twitching, nausea, rapid weight gain, seizures, stupor, swelling of the face, ankles, or hands, or unusual tiredness or weakness

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