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The prevalence of obesity in the United States has increased from 30.5% in 1999-2000 to 41.9% in 2017-2020

Bioorg Med Chem Lett 23:40114018 Cornell S (2012) Differentiating among incretin therapies: a multiple-target approach to type 2 diabetes

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Choquette et al.s 6-month intervention (3 sessions/week of combined resistance and aerobic exercise) in overweight/obese postmenopausal women found no improvements in whole-body, lumbar spine, or hip BMD (including total hip, femoral neck, trochanter, and Wards triangle)