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Tissue repair research sometimes pairs IGF-1 LR3 with BPC-157 and TB-500 to examine whether IGF1R-driven anabolism combined with angiogenesis (BPC-157) and cellular migration (TB-500) accelerates repair beyond what either mechanism produces alone

One trial 33 studied older adults over 40 days

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The hypothalamus releases natural GHRH to stimulate the pituitary directly, while a separate ghrelin pathway modulates the amplitude and timing of each secretory pulse