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In addition, the change of DNA methylation is rather different between early and late stage (294, 295)

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CJC-1295 is a long-acting analogue of growth hormone-releasing hormone (GHRH) that induces prolonged stimulation of growth hormone (GH) 1 and increased insulin-like growth factor-1 (IGF-1) secretion in humans

doi: 10.1155/2012/745483 5 Centers for Disease Control and Preventation (2016)

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Stopping rules: Discontinue GHK-Cu if free copper exceeds 25 mcg/dL, 24-hour urine copper exceeds 100 mcg/day, ALT or AST rises to more than 3 times the patient's baseline value, or clinical signs of copper toxicity appear