Both share the GLP-1 class side-effect profile, led by gastrointestinal symptoms: nausea, vomiting, diarrhea, and constipation, worst during dose increases
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BMJ 372 , n71 (2021) Higgins, J
The percentage of participants achieving clinically meaningful thresholds (5%, 10%, 15%, 20%+ weight loss) exceeded anything previously seen with GLP-1 based therapies
Additionally, semaglutide may increase your risk of biliary disease (cholelithiasis), diseases affecting the bile ducts, gallbladder and other structures involved in the production and transportation of bile (5)
At present, semaglutide is the only GLP-1 medication for type 2 diabetes available in pill form in the US